Rexonage3 is the latest innovation in regenerative medicine that uses patented QMR® technology to stimulate cell regeneration without generating heat or causing tissue damage, promoting true tissue regeneration without scar tissue.
Unlike other technologies such as RF, HIFU or laser, QMR® does not use heat or induced thermal damage. Instead, it uses high-frequency currents (4-64 MHz) to activate biological mechanisms that stimulate stem cell differentiation and regeneration of skin and other tissues [1, 4, 5].
How does it work?
Skin and Collagen activation: Regenerates skin by increasing type I and III collagen [3].
Modulation of inflammation: Powerful immediate anti-inflammatory effect [2].
Tissue regeneration: Stimulates mitosis and differentiation of mesenchymal stem cells (MSCs) [1].
It directly stimulates MSCs by activating metabolic pathways that induce natural tissue differentiation and regeneration [1]. As a result, an increase in dermal thickness of 0.2 - 0.3 mm has been observed [6] as well as an increase in collagen type I and III, the latter by up to 48% [3]. It also activates pathways related to extracellular matrix remodelling, collagen reorganisation, improvement of the regenerative microenvironment and angiogenesis [1].
CLINICAL APPLICATIONS
Aesthetic Medicine
-Improved skin elasticity and increased dermal thickness.
-Natural lifting effect on cheekbones, jawline and neck.
-Improved skin texture, tone and luminosity.
-Rejuvenation, reduction of wrinkles and expression lines.
-Treatment of stretch marks and body laxity.
Dermatology
-Treatment of inflammatory acne and acne scars.
-Management of inflammatory skin conditions such as dermatitis [10] and rosacea.
-Healing and tissue regeneration in burns and ulcers [11].
-Stimulation of dermal regeneration in damaged skin.
REFERENCES CLINICAL STUDIES
[1] Sella et al., Plos ONE 2018
[2] Paolucci et al., Antioxidants, 2023
[3] Eun Joo Baek et al., Wiley, 2023
[4] Regiani, C., et al., BAM, 200
